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Peptides — Growth Hormone Axis

GHRP-6

An earlier-generation hexapeptide GH secretagogue, historically important in the discovery of the ghrelin receptor.

Education Hub

Pre-clinical mechanism

GHS-R1a agonist; ghrelin-like activity in animal models, including transient orexigenic effects in rodents.

Key pre-clinical findings

  • Foundational rat pharmacology: GHRP-6 demonstrated growth-hormone release through a non-GHRH receptor, contributing to the identification of GHS-R/ghrelin (Bowers et al., 1984).

Primary literature

On the in vitro and in vivo activity of a new synthetic hexapeptide that acts on the pituitary to release growth hormone

Bowers CY, Momany F, Reynolds GA, Hong A · Endocrinology · 1984

Research and educational use only. This page summarises publicly available pre-clinical literature for educational and scientific reference. It is not medical, clinical, dosing or therapeutic advice. Nothing on this page implies that any VCP Australia product is approved, certified, safe, effective, suitable for a particular purpose, or intended for human or animal consumption.

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