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Peptides — Longevity & Mitochondrial

Humanin

A 24-amino-acid mitochondrial-derived peptide encoded within the 16S rRNA region of mtDNA, studied in pre-clinical cytoprotection research.

Education Hub

Pre-clinical mechanism

Cell-culture studies describe binding to the FPR2 and CNTFR-WSX-1-gp130 receptor complex and activation of STAT3, with anti-apoptotic effects in neuronal models.

Key pre-clinical findings

  • Cultured neurons exposed to amyloid-β: reduction in neurotoxicity and apoptotic markers (Hashimoto et al., 2001).

Primary literature

Research and educational use only. This page summarises publicly available pre-clinical literature for educational and scientific reference. It is not medical, clinical, dosing or therapeutic advice. Nothing on this page implies that any VCP Australia product is approved, certified, safe, effective, suitable for a particular purpose, or intended for human or animal consumption.

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