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Peptides — Immune & Anti-Microbial

KPV

A tripeptide corresponding to the C-terminal sequence of α-MSH, studied in pre-clinical models of intestinal inflammation.

α-MSH (11-13)Lysine-Proline-Valine

Education Hub

Pre-clinical mechanism

Cell and animal studies describe inhibition of NF-κB signalling and reduced pro-inflammatory cytokine release in intestinal epithelial cells.

Key pre-clinical findings

  • DSS-induced colitis mouse model: reduction in disease activity index and mucosal cytokine levels (Dalmasso et al., 2008).

Primary literature

Research and educational use only. This page summarises publicly available pre-clinical literature for educational and scientific reference. It is not medical, clinical, dosing or therapeutic advice. Nothing on this page implies that any VCP Australia product is approved, certified, safe, effective, suitable for a particular purpose, or intended for human or animal consumption.

Research-Use Notice

Products displayed on this website may be intended for laboratory, analytical or research purposes only where applicable. They are not intended to diagnose, treat, cure or prevent any disease. They are not supplied for human or animal consumption unless expressly stated and lawfully permitted. Customers are responsible for understanding and complying with all applicable laws and regulations. Product information is provided for informational purposes only and does not constitute medical advice.