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Peptides — Cognitive & Neuro

Semax

A synthetic heptapeptide analogue of ACTH(4-7) with a Pro-Gly-Pro extension, studied in Russian pre-clinical neuroprotection research.

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Pre-clinical mechanism

Animal models report increased expression of BDNF and NGF in the hippocampus and cortex, with neuroprotective effects in ischaemic and behavioural paradigms.

Key pre-clinical findings

  • Rat MCAO ischaemia model: reduced infarct size and improved neurological scores (Gusev et al., 2005).

Primary literature

Semax in prevention of disease progress and development of exacerbations in patients with cerebrovascular insufficiency

Gusev EI, Skvortsova VI, Miasoedov NF, et al. · Zhurnal Nevrologii i Psikhiatrii imeni S.S. Korsakova · 2005

Research and educational use only. This page summarises publicly available pre-clinical literature for educational and scientific reference. It is not medical, clinical, dosing or therapeutic advice. Nothing on this page implies that any VCP Australia product is approved, certified, safe, effective, suitable for a particular purpose, or intended for human or animal consumption.

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